The Institute for Biogenesis Research (IBR) is a Center of Biomedical Research Excellence (COBRE) that is focused on the study of mammalian developmental and reproductive biology, using mainly the mouse as a model with occasional forays into human reproduction. It is part of the John A. Burns School of Medicine (JABSOM) in the University of Hawaii at Manoa.
The Institute for Biogenesis Research (IBR) was formed in September of 2000 with the goal of establishing a research center of excellence for reproductive biology. The IBR’s founding director was National Academy of Sciences member, Dr. Ryuzo Yanagimachi. Currently, the IBR houses fourteen full time faculty, and more than 30 staff members. It holds more than $12 million in grant awards. The IBR gratefully acknowledges center funding from the NIGMS/NIH IDeA Program with its COBRE award (P20GM103457).
The major focus of the IBR’s research is reproductive and developmental biology, with an emphasis on assisted reproductive techniques (ART). IBR faculty use ART as a model to understand mammalian reproduction and development, and to develop new transgenic models for biomedical research. We also use animal models of ART to investigate and improve current ART usage in fertility clinics. Our research includes a wide range of studies from basic DNA structure to post-fertilization effects of ART on human embryonic development (see Figure).
