Resources

Mouse as a Model System and How to Breed Mice

• The Mouse as a Model System
• Managing A Mouse Colony
• Targeting Vector Design
• Introduction to Mouse Reproduction and the Postnatal Period from Lee Silver's Mouse Genetics
• The postnatal period
• UC Irvine University Transgenic Core guide to mouse breeding and reproduction
• University of Michigan Transgenic Core guide to breeding transgenic and knockout mice
• Jax Mouse Breeding Strategies Manua

Mouse Genome Sequence

• Ensemble Mouse Genome Server
• NCBI Entrez Mouse Genome Server
• UCSC Genome Browser Gateway

Molecular Genetics Resources

• AceView: gene annotation and alternative transcripts
• Functional Annotation of Mouse cDNAs Database (FANTOM)
• Cloning Vector Database - Addgene
• Jackson Genotyping Protocols
• Primer3 PCR Primer Picking Software

BAC Libraries

• BACPAC Resources (CHORI)
• Invitrogen

Mutant Repositories

Mutant Mice, Cryopreserved Embryos and ES cells

• International Mouse Strain Resource
• Mouse Genome Informatics at the Jackson LaboratoryMouse Genome Informatics at the Jackson LaboratoryMouse Genome Informatics at the Jackson Laboratory
• The Cre Portal: a database searchable by tissue specificity from MGIThe Cre Portal: a database searchable by tissue specificity from MGIThe Cre Portal: a database searchable by tissue specificity from MGI
• Knockout Mouse Project (KOMP) Repository
• Mutant Mouse Regional Resource Centers
• NCI Frederick Cancer Mouse Repository
• European Mouse Mutant Archive
• Riken BioResource Center, JapanRiken BioResource Center, JapanRiken BioResource Center, Japan
• Case Western Reserve University Cystic Fibrosis Mouse Models Core

Conditional Mutant and Cre Driver Archives and Databases

• Cre-X-Mice database at SLRICre-X-Mice database at SLRICre-X-Mice database at SLRI
• The Cre Portal: a database searchable by tissue specificity from MGIThe Cre Portal: a database searchable by tissue specificity from MGIThe Cre Portal: a database searchable by tissue specificity from MGI

International Gene Trap Consortium

• Texas A&M Institute of Genomic Medicine (TIGM)
• European Conditional Mouse Mutagenesis Program (EUCOMM)

Phenotype-driven Screens for Variants

• Phenotypes and Mutants Community Resources at JaxPhenotypes and Mutants Community Resources at Jax
• Large Scale Mutagenesis Program, Riken, JapanLarge Scale Mutagenesis Program, Riken, Japan
• Neuroscience Mutagenesis Facility at Jackson LaboratoryNeuroscience Mutagenesis Facility at Jackson Laboratory
• Mouse Heart, Lung, Blood, and Sleep Disorders Center at Jackson LaboratoryMouse Heart, Lung, Blood, and Sleep Disorders Center at Jackson Laboratory
• Harwell ENU Mutagenesis Program, EnglandHarwell ENU Mutagenesis Program, England
• Sloan-Kettering Mouse Mutagenesis
• Mouse Mutagenesis Center for Developmental Defects, Baylor College of MedicineMouse Mutagenesis Center for Developmental Defects, Baylor College of Medicine

Transgenic Mouse Repository

• Gensat generates BAC transgenic mice to express Cre or EGFP in specific neuronal populations.Gensat generates BAC transgenic mice to express Cre or EGFP in specific neuronal populations.

Genetically Engineered Mouse/ES Cell Clone Resources

• NIH KnockOut Mouse Project (KOMP)
• International Knockout Mouse Phenotyping Consortium (IMPC)
• Unitrap Database of Gene Trapped ES Cell Clones
• Canadian Mouse Mutant Repository (CMMR)
• Center for AnimalResources and Development Database (CARD)
• Japan Mouse/Rat Strain Resources Database
• RIKEN BioResource Centers
• Taconic Knockout Repository
• CMHD Mutagenesis Core and Gene Trap Core
• German Gene Trap Consortium
• International Mouse Mutagenesis Consortium (IMMC)
• Riken Large Scale Mutagenesis Project
• Stem Cells at the National Academies

More Mouse Databases - Cre or Conditional Mice

• Brian Condie's Cre Transgenic Database
• Cre Mouse Portal at The Jackson Laboratory
• Andras Nagy's Cre-X-Mice: A Database of Cre Transgenic Lines
• Mouse Cre Database at the Institut Clinique de la Souris
• The Jackson Laboratory Induced Mutant Resource

Commercial DNA Cloning and Genotyping Services

Vector Construction

• GenScript Corporation
• inGenious
• InvivoGen
• OzGene
• Vega Biolab
• Cyagen

Transgenics

• genOway
• OzGene
• Cyagen

Gene Targeting

• genOway
• inGenious
• OzGene
• Cyagen

Commercial DNA Cloning and Genotyping Services

Genotyping

• Embark Scientific

DNA and Gene Cloning Services

• Bio Basic
• Blue Sky Biotech
• Gene Bridges
• Genscript
• Hypromatix
• Invivogen
• Origene

Mouse Genetics

• "The Coat Colors of Mice" by Willys K. Silvers
• Inbred Strains of Rats and Mice, a reference resource at the Jackson Laboratory
• Origins of Inbred Mice Edited by Robert C Morse III
• emap, the edinburgh mouse atlas project
• Biology of the Laboratory Mouse
• The Anatomy of the Laboratory Mouse
• Atlas of Neoplastic and Non-neoplastic Lesions

Rodent Pathology and Medicine

• Biology of the Laboratory Mouse
• Atlas of Neoplastic and Non-neoplastic Lesions
• Pathbase a mouse pathology database at the University of Cambridge
• Guidelines for assessing the health and condition of mice by Folz and Ullman Collere
• The American Committee on Laboratory Animal Diseases (ACLAD) has a web site with useful information on treatment and diagnosis of diseases which affect laboratory animals, and access to an archive of their newsletters.
• Veterinary Formulary, guidance on drug dosages for different species from the University of Minnesota.
• Companion Guide to Infectious Diseases of Mice and Rats

More Mouse Databases - Cre or Conditional Mice

• Brian Condie's Cre Transgenic Database
• Cre Mouse Portal at The Jackson Laboratory
• Andras Nagy's Cre-X-Mice: A Database of Cre Transgenic Lines
• Cre Zoo Database at the Fleming Institute
• International Mouse Strain Resource
• The Jackson Laboratory Induced Mutant Resource
• International Mouse Strain Resource

Mouse Biology Resources

• NetVet: Rodents
• Whole Mouse Catalog
• Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research
• Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research
• Guide for the Care and Use of Laboratory Animals Eighth Edition (2011)

Online Atlases of Mouse Developmental Anatomy

• Edinburgh Mouse Atlas Project (EMAP)
• Duke Center for In Vivo Microscopy Mouse Atlas
• Mouse Biomedical Research Informatics Network (BIRN) Atlasing Toolkit
• The Virtual Embryo
• Savolainen SM, Foley JF, Elmore SA. 2009. Histology atlas of the developing mouse heart with emphasis on E11.5 to E18.5. Toxicol Pathol. 37:395-414
• Allen Institute for Brain Science: Developing Mouse Brain Atlas
• The Electronic Prenatal Mouse Brain Atlas
• Vista Transgenic Enhancer Atlas of the Developing Telencephalon
• Vascular Atlas of the Developing Mouse Embryo

Mouse Courses

• Molecular Embryology of the Mouse, Cold Spring Harbor Laboratory