Institute for Biogenesis Research University of Hawaii John A. Burns School of Medicine

Supported by IBR-COBRE (Center of Biomedical Research Excellence) IDeA Program NCRR 5P20RR024206-01, NIGMS 8P20GM103457-05

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About Us Overview The Institute for Biogenesis Research (IBR) was formed in September of 2000 with the goal of establishing a research center of excellence for reproductive biology. The IBR was intended to build on the 40-year career of one of the leaders in this field, Dr. Ryuzo Yanagimachi, who served as the IBR's founding Director from 2000 to 2005. Currently, the IBR houses eight full time faculty, and more than 30 staff members. It holds more than $12 million in grant awards. Research The major focus of the IBR's research is reproductive and developmental biology, with an emphasis on assisted reproductive techniques (ART). IBR faculty use ART as a model to understand mammalian reproduction and development, and to develop new transgenic models for biomedical research. We also use animal models of ART to investigate and improve current ART usage in fertility clinics. Our research includes a wide range of studies from basic DNA structure to post-fertilization effects of ART on human embryonic development (see Figure).