About Us

Welcome to the Institute for Biogenesis Research

The IBR was founded in September of 2000 with the opening of a new research facility on the University of Hawaii at Manoa campus. The institute was built in honor of one of the university’s most distinguished scientists, Dr. Ryuzo Yanagimachi, whose forty year career included so many significant advances in reproduction that they are too numerous to mention, here.The IBR’s purpose was to attract a group of scientists to develop a world class center for the study of reproductive biology built on Dr. Yanagimachi’s work. During the next seven years, seven new faculty were recruited, and the expertise of the IBR now spans a broad range of reproductive biology.


The Institute for Biogenesis Research (IBR) was formed in September of 2000 with the goal of establishing a research center of excellence for reproductive biology. The IBR was intended to build on the 40-year career of one of the leaders in this field, Dr. Ryuzo Yanagimachi, who served as the IBR’s founding Director from 2000 to 2005. Currently, the IBR houses eight full time faculty, and more than 30 staff members. It holds more than $12 million in grant awards.

The major focus of the IBR’s research is reproductive and developmental biology, with an emphasis on assisted reproductive techniques (ART). IBR faculty use ART as a model to understand mammalian reproduction and development, and to develop new transgenic models for biomedical research. We also use animal models of ART to investigate and improve current ART usage in fertility clinics. Our research includes a wide range of studies from basic DNA structure to post-fertilization effects of ART on human embryonic development (see Figure).